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When will PYC Therapeutics Limited (ASX:PYC) be profitable?

We think now is a good time to analyze PYC Therapeutics Limited (ASX:PYC) It seems that the company may be on the cusp of a significant business achievement. PYC Therapeutics Limited, a pharmaceutical development company, is engaged in the discovery and development of novel RNA therapeutics for the treatment of genetic diseases in Australia. The AU$994m market-cap company announced its latest loss of AU$50m for its latest financial year results to 30 June 2025. As the path to profitability is a topic on the minds of PYC Therapeutics investors, we decided to gauge market sentiment. We’ve put together a brief outline of industry analyst expectations for the company, its breakeven year and its implied growth rate.

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According to 4 industry analysts covering PYC Therapeutics, the consensus is that breakeven is near. They estimate the company will make its final loss in 2027 before turning a positive profit of AU$100 million in 2028. Therefore, it is estimated that the company will breakeven in about 2 years after the next 2 years. To meet this breakeven date, we calculated the rate at which the company would have to grow year-on-year. It expects an average annual growth rate of 28%, indicating high confidence from analysts. If this rate turns out to be too aggressive, the company may become profitable much later than analysts’ predictions.

ASX:PYC Earnings Per Share Growth Jan 16, 2026

The underlying developments driving PYC Therapeutics’ growth are not the focus of this comprehensive overview, but keep in mind that biotechs typically have erratic periods of cash flow depending on the stage of product development. This means that high growth rates are not unusual, especially if the company is currently in an investment period.

Check out our latest analysis for PYC Therapeutics

One thing we’d like to point out is that PYC Therapeutics has no debt on its balance sheet, which is highly unusual for a cash-burning biotech, which typically has high levels of debt relative to its equity. This means that the company is operating purely on its equity investment and is not burdened with debt. This aspect reduces the risk of investing in a loss-making company.

There are key fundamentals of PYC therapeutics that are not covered in this article, but we must emphasize again that this is only a basic overview. For a more comprehensive look at PYC Therapeutics, visit the PYC Therapeutics company page at Simply Wall St. We’ve also compiled a list of essential elements you should look out for:

  1. Evaluation: What is PYC Therapeutics worth today? Is future growth potential already factored into the price? The intrinsic value infographic in our free research report helps visualize whether PYC Therapeutics is currently mispriced by the market.

  2. Management team: An experienced management team at the helm adds to our confidence in the business – see who sits behind the board and CEO of PYC Therapeutics.

  3. Other top performing stocks: Are there other stocks that offer better prospects with proven track records? Explore our free list of these great stocks here.

Have feedback on this article? Worried about content? Stay in touch Live with us. Alternatively, email editorial team (at) simplywallst.com.

This article by Simply Wall St. is general in nature. We only provide commentary using an unbiased methodology based on historical data and analyst forecasts and our articles are not intended to be financial advice. It does not recommend buying or selling any stock, and does not take into account your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative content. Simply Wall St. has no position in any of the stocks mentioned.

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